Protein Name corticotropin releasing hormone receptor 1
Organism Rattus norvegicus
Gene ID 58959
Gene Symbol

Crhr1

UniProt P35353 (CRFR1_RAT), B3SXS3 (B3SXS3_RAT)
Relationships Total Number of functionally related compound(s) : 161
Total Number of Articles : 267
Description

corticotropin releasing hormone receptor 1

Gene Summary

This gene encodes a member of the G-protein coupled receptor family. The encoded protein is a receptor for corticotropin-releasing factor (CRH) and urocortin (UCN). The interaction of this protein with CRH and UCN triggers G-protein coupled signaling. This protein plays a pivotal role in mediating the CRH-elicited effects in depression and anxiety. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

synonyms
  • corticotropin-releasing factor receptor 1
  • corticotrophin releasing hormone receptor 1
  • corticotropin releasing hormone 1
Click to show/hide the synonyms
Properties