Title : Hyper-activated motility in sperm capacitation is mediated by phospholipase D-dependent actin polymerization.

Pub. Date : 2012 Feb 15

PMID : 22178154






2 Functional Relationships(s)
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Protein Name
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1 Inhibition of Phosphatidic Acid (PA) formation by PLD using butan-1-ol, inhibited actin polymerization and motility, as well as in vitro fertilization (IVF) and the ability of the sperm to undergo the AR. Butanols glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
2 The inhibition of sperm HAM by low concentration of butan-1-ol is completely restored by adding PA, further indicating the involvement of PLD in these processes. Butanols glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens