Title : Inhibition of glycoprotein synthesis in the endoplasmic reticulum as a novel anticancer mechanism of (-)-epigallocatechin-3-gallate.

Pub. Date : 2011 Nov-Dec

PMID : 22162335






1 Functional Relationships(s)
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1 Collectively, our results support that glucosidase II inhibitor EGCG interferes with protein processing and quality control in the ER, which diverts tyrosinase, VEGF, and likely other glycoproteins towards proteasomal degradation. epigallocatechin gallate tyrosinase Homo sapiens