Pub. Date : 2012 May
PMID : 22160932
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | After 4 h, neuronal cell death induced by ketamine was associated with the induction of Bax, release of cytochrome c into the cytosol, and activation of caspase-3. | Ketamine | caspase 3 | Rattus norvegicus |
| 2 | One single dose of 1 mg/g nicotinamide was administered to a developing rat and was found to inhibit ketamine-induced neuroapoptosis by downregulating Bax, inhibiting cytochrome c release from mitochondria into cytosol, and inhibiting the expression of activated caspase-3. | Ketamine | caspase 3 | Rattus norvegicus |