Pub. Date : 2012 Jul
PMID : 22149137
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The Hsp90 inhibitor SNX-7081 synergizes with and restores sensitivity to fludarabine in chronic lymphocytic leukemia cells with lesions in the TP53 pathway: a potential treatment strategy for fludarabine refractory disease. | fludarabine | tumor protein p53 | Homo sapiens |
2 | The Hsp90 inhibitor SNX-7081 synergizes with and restores sensitivity to fludarabine in chronic lymphocytic leukemia cells with lesions in the TP53 pathway: a potential treatment strategy for fludarabine refractory disease. | fludarabine | tumor protein p53 | Homo sapiens |
3 | In seven cell lines and 23 patient samples synergy between SNX-7081 and fludarabine (2-FaraA) was apparent in the three TP53 mutated cell lines and at significantly lower concentrations in TP53 or ATM dysfunctional patient cells. | fludarabine | tumor protein p53 | Homo sapiens |
4 | In seven cell lines and 23 patient samples synergy between SNX-7081 and fludarabine (2-FaraA) was apparent in the three TP53 mutated cell lines and at significantly lower concentrations in TP53 or ATM dysfunctional patient cells. | fludarabine | tumor protein p53 | Homo sapiens |