PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22149137-0 2012 The Hsp90 inhibitor SNX-7081 synergizes with and restores sensitivity to fludarabine in chronic lymphocytic leukemia cells with lesions in the TP53 pathway: a potential treatment strategy for fludarabine refractory disease. fludarabine 73-84 tumor protein p53 Homo sapiens 143-147 22149137-0 2012 The Hsp90 inhibitor SNX-7081 synergizes with and restores sensitivity to fludarabine in chronic lymphocytic leukemia cells with lesions in the TP53 pathway: a potential treatment strategy for fludarabine refractory disease. fludarabine 192-203 tumor protein p53 Homo sapiens 143-147 22149137-4 2012 In seven cell lines and 23 patient samples synergy between SNX-7081 and fludarabine (2-FaraA) was apparent in the three TP53 mutated cell lines and at significantly lower concentrations in TP53 or ATM dysfunctional patient cells. fludarabine 72-83 tumor protein p53 Homo sapiens 120-124 22149137-4 2012 In seven cell lines and 23 patient samples synergy between SNX-7081 and fludarabine (2-FaraA) was apparent in the three TP53 mutated cell lines and at significantly lower concentrations in TP53 or ATM dysfunctional patient cells. fludarabine 85-92 tumor protein p53 Homo sapiens 120-124