Title : Cyanidin-3-glucoside suppresses TNF-α-induced cell proliferation through the repression of Nox activator 1 in mouse vascular smooth muscle cells: involvement of the STAT3 signaling.

Pub. Date : 2012 Mar

PMID : 22120492






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Then, we found that C3G attenuated TNF-alpha-induced ROS over generation by Dihydroethidium staining. ros tumor necrosis factor Mus musculus
2 Administration of the ROS scavenger catalase (2,000 U/ml) remarkably inhibited TNF-alpha-induced cell proliferation and STAT3 activation. ros tumor necrosis factor Mus musculus
3 These data suggest that C3G exerts its antiproliferative effect on TNF-alpha-induced VSMCs proliferation through inhibiting STAT3 activation by attenuating NoxA1-derived ROS over production. ros tumor necrosis factor Mus musculus