Title : Lobeline attenuates neonatal ethanol-mediated changes in hyperactivity and dopamine transporter function in the prefrontal cortex in rats.

Pub. Date : 2012 Mar 29

PMID : 22119644






3 Functional Relationships(s)
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1 In the current study, lobeline, which interacts with proteins in dopaminergic presynaptic terminals, was evaluated for its ability to attenuate neonatal ethanol-induced locomotor hyperactivity and alterations in dopamine transporter (DAT) function in striatum and prefrontal cortex (PFC). Lobeline solute carrier family 6 member 3 Rattus norvegicus
2 In the current study, lobeline, which interacts with proteins in dopaminergic presynaptic terminals, was evaluated for its ability to attenuate neonatal ethanol-induced locomotor hyperactivity and alterations in dopamine transporter (DAT) function in striatum and prefrontal cortex (PFC). Lobeline solute carrier family 6 member 3 Rattus norvegicus
3 Thus, lobeline and methylphenidate differentially altered DAT function following neonatal ethanol exposure. Lobeline solute carrier family 6 member 3 Rattus norvegicus