Pub. Date : 2012 May
PMID : 22114872
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | METHODS: Using human embryonic kidney 293 (HEK293) cells stably expressing OATP1B1, we observed the effect of quercetin on OATP1B1-mediated uptake of estrone-3-sulphate (E3S) and pravastatin. | estrone sulfate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 2 | METHODS: Using human embryonic kidney 293 (HEK293) cells stably expressing OATP1B1, we observed the effect of quercetin on OATP1B1-mediated uptake of estrone-3-sulphate (E3S) and pravastatin. | estrone sulfate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 3 | METHODS: Using human embryonic kidney 293 (HEK293) cells stably expressing OATP1B1, we observed the effect of quercetin on OATP1B1-mediated uptake of estrone-3-sulphate (E3S) and pravastatin. | estrone sulfate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 4 | CONCLUSIONS: These findings suggest that quercetin inhibits the OATP1B1-mediated transport of E3S and pravastatin in vitro and also has a modest inhibitory influence on the pharmacokinetics of pravastatin in healthy Chinese-Han male volunteers. | estrone sulfate | solute carrier organic anion transporter family member 1B1 | Homo sapiens |