Title : Association of hOGG1 and XPD polymorphisms with urothelial carcinoma in Taiwan.

Pub. Date : 2011 Nov

PMID : 22110223






2 Functional Relationships(s)
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1 Those who had a history of cigarette smoking and alcohol consumption carrying both the hOGG1 and XPD risk genotypes had the highest UC risk (OR=9.9, 95% CI= 4.5-21.8). Alcohols 8-oxoguanine DNA glycosylase Homo sapiens
2 CONCLUSION: A significant joint effect of cigarette smoking, alcohol consumption and both hOGG1 and XPD risk genotypes increases UC risk and UC cases carrying both hOGG1 and XPD risk genotypes have a significantly greater risk of high grade tumor. Alcohols 8-oxoguanine DNA glycosylase Homo sapiens