Title : Combined α7 nicotinic acetylcholine receptor agonism and partial serotonin transporter inhibition produce antidepressant-like effects in the mouse forced swim and tail suspension tests: a comparison of SSR180711 and PNU-282987.

Pub. Date : 2012 Jan

PMID : 22108649






1 Functional Relationships(s)
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1 Monoamine release is facilitated by nAChR stimulation, and nicotine-evoked serotonin (5-HT) release has been shown to depend on alpha7 nAChR activation. Serotonin cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus