Title : Inflammatory stress exacerbates hepatic cholesterol accumulation via disrupting cellular cholesterol export.

Pub. Date : 2012 May

PMID : 22098164






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 CONCLUSIONS: Inflammation disrupted PPAR-LXR-CYP7A1/ABCA1-mediated bile acid synthesis and cholesterol efflux resulting in exacerbated cholesterol accumulation in livers of C57BL/6J mice and HepG2 cells. Cholesterol peroxisome proliferator activated receptor alpha Mus musculus