Title : High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives.

Pub. Date : 2011 Dec 6

PMID : 22095230






1 Functional Relationships(s)
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1 Treatment of nonpigmented cells with vitamin D3 derivatives inhibited NF-kappaB DNA binding and NF-kappaB-dependent reporter assays, as well as inhibited the nuclear translocation of the p65 NF-kappaB subunit and its accumulation in the cytoplasm. Cholecalciferol RELA proto-oncogene, NF-kB subunit Homo sapiens