Title : Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway.

Pub. Date : 2011 Dec 6

PMID : 22089237






1 Functional Relationships(s)
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1 We demonstrate that EGFR transactivation and downstream ERK activation depends on increased shedding of heparin-binding EGF. Heparin epidermal growth factor receptor Homo sapiens