Title : Antidepressant-like effect of sildenafil through oxytocin-dependent cyclic AMP response element-binding protein phosphorylation.

Pub. Date : 2012 Jan 3

PMID : 22088430






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sildenafil increased the phosphorylation of cAMP response element-binding protein (CREB) in the hippocampus. Sildenafil Citrate cAMP responsive element binding protein 1 Mus musculus
2 Sildenafil increased the phosphorylation of cAMP response element-binding protein (CREB) in the hippocampus. Sildenafil Citrate cAMP responsive element binding protein 1 Mus musculus
3 The OTR antagonist inhibited sildenafil-induced CREB phosphorylation and sildenafil had no effect on CREB phosphorylation in OTR KO mice. Sildenafil Citrate cAMP responsive element binding protein 1 Mus musculus