Title : The complex interplay between cyclooxygenase-2 and angiotensin II in regulating kidney function.

Pub. Date : 2012 Jan

PMID : 22080858






1 Functional Relationships(s)
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1 RECENT FINDINGS: Normal rats with increased COX-2 activity but with different intrarenal Ang II activity because of sodium restriction or chronic treatment with angiotensin-converting enzyme (ACE) inhibitors showed similar renal hemodynamic responses to COX-2-selective inhibition (nimesulide) indicating independence from the intrarenal Ang II activity. Sodium angiotensinogen Rattus norvegicus