Title : LBH-589 (panobinostat) potentiates fludarabine anti-leukemic activity through a JNK- and XIAP-dependent mechanism.

Pub. Date : 2012 Apr

PMID : 22074700






1 Functional Relationships(s)
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1 These studies highlight the interplay between NF-kappaB activation, XIAP down-regulation, and JNK activation in anti-leukemic synergism between fludarabine and LBH-589. fludarabine X-linked inhibitor of apoptosis Homo sapiens