Pub. Date : 2011 Nov 15
PMID : 22033475
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, ovatodiolide can suppress activation of c-Jun N-terminal kinase, p38 mitogen-activated protein kinase, phosphatidylinositol 3-kinase and Akt, while it did not affect phosphorylation of extracellular signal regulating kinases (ERK)1/2. | ovatodiolide | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Taken together, these results demonstrate that ovatodiolide inhibits the metastatic ability of MDA-MB-231 cells by reducing MMP-9 activity through suppressing JNK, p38 MAPK and PI3K/Akt signaling pathways and inhibiting NF-kappaB activity. | ovatodiolide | mitogen-activated protein kinase 1 | Homo sapiens |