Title : Identification and structural characterization of novel genetic elements in the HIV-1 V3 loop regulating coreceptor usage.

Pub. Date : 2011

PMID : 22024519






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 N7K significantly increases the distance between V3 position 7 and sulphotyrosine at CCR5 position 14 (crucial for binding to gp120; from 4.22 A to 8.30 A), thus abrogating the interaction between these two important residues. sulphotyrosine C-C motif chemokine receptor 5 Homo sapiens