Title : Thrombin-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein disulfide-isomerase.

Pub. Date : 2012 Feb 1

PMID : 22013897






2 Functional Relationships(s)
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1 We conclude that PDI regulates thrombin-induced shedding of N60 and exposure of the TEM5 RGD motif by catalysing the reduction of crucial disulfide bonds of TEM5 on the cell surface. Disulfides adhesion G protein-coupled receptor A2 Homo sapiens
2 We conclude that PDI regulates thrombin-induced shedding of N60 and exposure of the TEM5 RGD motif by catalysing the reduction of crucial disulfide bonds of TEM5 on the cell surface. Disulfides adhesion G protein-coupled receptor A2 Homo sapiens