Title : Reactive-oxygen-species-mediated Cdc25C degradation results in differential antiproliferative activities of vanadate, tungstate, and molybdate in the PC-3 human prostate cancer cell line.

Pub. Date : 2012 Feb

PMID : 22012316






1 Functional Relationships(s)
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1 The results demonstrate that all of the three oxoanions can cause G(2)/M cell cycle arrest, which is evidenced by the increase in the level of phosphorylated Cdc2 at its inactive Tyr-15 site. Tyrosine cyclin dependent kinase 1 Homo sapiens