Pub. Date : 2012 Mar
PMID : 22011930
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer. | Lapatinib | erb-b2 receptor tyrosine kinase 2 | Mus musculus |
| 2 | PURPOSE: Lapatinib, a small molecule EGFR/HER2 inhibitor, partially inhibits the outgrowth of HER2+ brain metastases in preclinical models and in a subset of CNS lesions in clinical trials of HER2+ breast cancer. | Lapatinib | erb-b2 receptor tyrosine kinase 2 | Mus musculus |
| 3 | PURPOSE: Lapatinib, a small molecule EGFR/HER2 inhibitor, partially inhibits the outgrowth of HER2+ brain metastases in preclinical models and in a subset of CNS lesions in clinical trials of HER2+ breast cancer. | Lapatinib | erb-b2 receptor tyrosine kinase 2 | Mus musculus |
| 4 | PURPOSE: Lapatinib, a small molecule EGFR/HER2 inhibitor, partially inhibits the outgrowth of HER2+ brain metastases in preclinical models and in a subset of CNS lesions in clinical trials of HER2+ breast cancer. | Lapatinib | erb-b2 receptor tyrosine kinase 2 | Mus musculus |