Title : NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.

Pub. Date : 2011 Dec

PMID : 22005259






3 Functional Relationships(s)
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Protein Name
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1 NF-kappaB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G2/M cell cycle arrest. tubeimoside I nuclear factor kappa B subunit 1 Homo sapiens
2 Moreover, tubeimoside-1 induced accumulation of reactive oxygen species and arrested cell cycle at the G(2)/M phase, thus contributing to apoptosis, through signaling regulation by tumor necrosis factor alpha, nuclear factor kappaB (NF-kappaB), Jun N-terminal kinase (JNK) and p53. tubeimoside I nuclear factor kappa B subunit 1 Homo sapiens
3 Moreover, tubeimoside-1 induced accumulation of reactive oxygen species and arrested cell cycle at the G(2)/M phase, thus contributing to apoptosis, through signaling regulation by tumor necrosis factor alpha, nuclear factor kappaB (NF-kappaB), Jun N-terminal kinase (JNK) and p53. tubeimoside I nuclear factor kappa B subunit 1 Homo sapiens