Pub. Date : 2012 Sep
PMID : 21993632
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this study was to investigate the expression profile of miR-101 and its target gene Mcl-1 in NSCLC and to assess their clinical significance. | mir-101 | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 2 | Down-regulation of miR-101 was associated with overexpression of Mcl-1 mRNA in NSCLC tissue when compared with corresponding normal tissue, with a negative correlation (r = -0.724, P < 0.01). | mir-101 | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
| 3 | Our results suggest that down-regulation of miR-101 may result in enhanced expression of Mcl-1 in NSCLC, which consequently favored tumor progression. | mir-101 | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |