Title : Amelioration of hypertriglyceridemia with hypo-alpha-cholesterolemia in LPL deficient mice by hematopoietic cell-derived LPL.

Pub. Date : 2011

PMID : 21980507






5 Functional Relationships(s)
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1 Liver triglyceride content in LPL+/+ LPL-/- mice was also significantly increased, compared with LPL-/- LPL-/- mice (6.8+-0.7 vs. 4.6+-0.5 mg/g wet tissue, p<0.05, n = 6). Triglycerides lipoprotein lipase Mus musculus
2 Liver triglyceride content in LPL+/+ LPL-/- mice was also significantly increased, compared with LPL-/- LPL-/- mice (6.8+-0.7 vs. 4.6+-0.5 mg/g wet tissue, p<0.05, n = 6). Triglycerides lipoprotein lipase Mus musculus
3 Liver triglyceride content in LPL+/+ LPL-/- mice was also significantly increased, compared with LPL-/- LPL-/- mice (6.8+-0.7 vs. 4.6+-0.5 mg/g wet tissue, p<0.05, n = 6). Triglycerides lipoprotein lipase Mus musculus
4 Liver triglyceride content in LPL+/+ LPL-/- mice was also significantly increased, compared with LPL-/- LPL-/- mice (6.8+-0.7 vs. 4.6+-0.5 mg/g wet tissue, p<0.05, n = 6). Triglycerides lipoprotein lipase Mus musculus
5 CONCLUSIONS: Hematopoietic cell-derived LPL could efficiently ameliorate severe hypertriglyceridemia and hypo-alpha-cholesterolemia at the compensation of increased triglyceride content of liver in LPL-/- mice. Triglycerides lipoprotein lipase Mus musculus