Title : Decreased NADPH oxidase expression and antioxidant activity in cachectic skeletal muscle.

Pub. Date : 2011 Sep

PMID : 21966644






1 Functional Relationships(s)
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1 RESULTS: Superoxide levels increased 1.4-fold in the muscle of mice with cancer cachexia, and this was associated with a decrease in mRNA of NOX enzyme subunits, NOX2, p40(phox) and p67(phox) along with the antioxidant enzymes SOD1, SOD2 and GPx. Superoxides superoxide dismutase 1, soluble Mus musculus