Title : Modulation of multidrug efflux pump activity by new hydantoin derivatives on colon adenocarcinoma cells without inducing apoptosis.

Pub. Date : 2011 Oct

PMID : 21965738






1 Functional Relationships(s)
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1 Previously, we demonstrated that eight hydantoin derivatives inhibited the P-glycoprotein (ABCB1) efflux pump of mouse T-lymphoma cells, as well as acting synergistically with the anticancer drug doxorubicin. Hydantoins ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus