Title : Oleuropein and hydroxytyrosol inhibit adipocyte differentiation in 3 T3-L1 cells.

Pub. Date : 2011 Nov 7

PMID : 21945192






2 Functional Relationships(s)
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1 PPARgamma, C/EBPalpha and SREBP-1c transcription factors and their downstream targets genes (GLUT4, CD36 and FASN) were down-regulated after treatment by oleuropein and hydroxytyrosol. 3,4-dihydroxyphenylethanol sterol regulatory element binding transcription factor 1 Mus musculus
2 Furthermore, oleuropein and its derivate hydroxytyrosol decreased the transcriptional activity of SREBP-1c in a stable transfected 3T3-L1 cell line. 3,4-dihydroxyphenylethanol sterol regulatory element binding transcription factor 1 Mus musculus