Title : Opposing roles for cannabinoid receptor type-1 (CB₁) and transient receptor potential vanilloid type-1 channel (TRPV1) on the modulation of panic-like responses in rats.

Pub. Date : 2012 Jan

PMID : 21937980






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Given the cellular and behavioral evidence suggesting opposite functions for cannabinoid type 1 receptor (CB1) and transient receptor potential vanilloid type-1 channel (TRPV1), we hypothesized that they could differentially influence panic-like reactions induced by electrical stimulation of the dPAG. dpag transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus
2 Given the cellular and behavioral evidence suggesting opposite functions for cannabinoid type 1 receptor (CB1) and transient receptor potential vanilloid type-1 channel (TRPV1), we hypothesized that they could differentially influence panic-like reactions induced by electrical stimulation of the dPAG. dpag transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus
3 Supporting this view, we observed that several neurons in the dPAG co-expressed CB1 and TRPV1. dpag transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus