Title : TLR signaling-mediated differential histone modification at IL-10 and IL-12 promoter region leads to functional impairments in tumor-associated macrophages.

Pub. Date : 2011 Dec

PMID : 21926109






1 Functional Relationships(s)
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1 Although, TRIF-mediated signal inducers, lipopolysaccharide or poly (I:C), induced high level of extracellular signal-regulated kinase (ERK)-1/2 mitogen-activated protein kinase (MAPK) phosphorylation, but they were failed to induce significant p38MAPK phosphorylation in TAM. Poly I-C TIR domain containing adaptor molecule 1 Homo sapiens