Title : Iron reduction by deferoxamine leads to amelioration of adiposity via the regulation of oxidative stress and inflammation in obese and type 2 diabetes KKAy mice.

Pub. Date : 2012 Jan 1

PMID : 21917632






1 Functional Relationships(s)
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1 Superoxide production and NADPH oxidase activity in fat, as well as urinary 8-hydroxy-2"-deoxyguanosine excretion, were decreased in KKAy mice after DFO treatment while p22(phox) expression in adipose tissue was diminished in such mice. Deferoxamine dynein cytoplasmic 1 heavy chain 1 Mus musculus