| Protein Name | dynein cytoplasmic 1 heavy chain 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13424 |
| Gene Symbol | Dync1h1 |
| UniProt | Q9JHU4 (DYHC1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
52
Total Number of Articles : 54 |
Description |
dynein cytoplasmic 1 heavy chain 1 |
| Gene Summary |
Enables dynein light intermediate chain binding activity. Involved in P-body assembly; positive regulation of cold-induced thermogenesis; and stress granule assembly. Located in cytoplasm and filopodium. Is expressed in several structures, including central nervous system; early conceptus; neural retina; placenta; and trigeminal nerve. Used to study Charcot-Marie-Tooth disease axonal type 2O. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2O; autosomal dominant intellectual developmental disorder 13; and spinal muscular atrophy with lower extremity predominant 1. Orthologous to human DYNC1H1 (dynein cytoplasmic 1 heavy chain 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |