Pub. Date : 2011 Nov 10
PMID : 21911836
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lateral self-association of VWF involves the Cys2431-Cys2453 disulfide/dithiol in the C2 domain. | dithiol | von Willebrand factor | Homo sapiens |
| 2 | Our present findings imply that lateral VWF dimers form when a Cys2431 thiolate anion attacks the Cys2431 sulfur atom of the Cys2431-Cys2453 disulfide bond of another VWF molecule, whereas the Cys2451-Cys2468 disulfide/dithiol mediates formation of trimers and higher-order oligomers. | dithiol | von Willebrand factor | Homo sapiens |
| 3 | Our present findings imply that lateral VWF dimers form when a Cys2431 thiolate anion attacks the Cys2431 sulfur atom of the Cys2431-Cys2453 disulfide bond of another VWF molecule, whereas the Cys2451-Cys2468 disulfide/dithiol mediates formation of trimers and higher-order oligomers. | dithiol | von Willebrand factor | Homo sapiens |