Title : Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands.

Pub. Date : 2011 Nov 4

PMID : 21911496






1 Functional Relationships(s)
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1 Using rosiglitazone as a model PPARgamma agonist, which decreased TNFalpha-induced high mannose N-glycan expression, we demonstrate a role for these carbohydrate residues in THP-1 rolling and adhesion that is independent of endothelial surface adhesion molecule expression (ICAM-1 and E-selectin). Carbohydrates peroxisome proliferator activated receptor gamma Homo sapiens