Title : Molecular basis of α1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer.

Pub. Date : 2011 Sep 30

PMID : 21909074






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Disulphide-trapping and antibody-binding studies further demonstrate that runaway C-terminal domain swapping, rather than the s4A/s5A domain swap previously proposed, underlies polymerization of the common Z-mutant of alpha1AT in vivo. disulphide serpin family A member 1 Homo sapiens