| Protein Name | serpin family A member 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 5265 |
| Gene Symbol | SERPINA1 |
| UniProt | P01009 (A1AT_HUMAN), E9KL23 (E9KL23_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
799
Total Number of Articles : 1314 |
Description |
serpin family A member 1 |
| Gene Summary |
The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2020] |
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