Title : MicroRNAs in the regulation of interfacial behaviors of MSCs cultured on microgrooved surface pattern.

Pub. Date : 2011 Dec

PMID : 21890196






1 Functional Relationships(s)
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1 Compared to MSCs cultured on the smooth substrates, MSCs incubated on microgrooved PHBHHx substrates showed increased expression of osteogenesis-related marker genes including cbfa1, col1a1 and bmp2, and decreased expression of vcl, vinculin encoding gene, adipogenesis-related genes including lpl, des and acta2, as well as myogenesis-related genes of myh11 and nse. poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) RUNX family transcription factor 2 Homo sapiens