Title : Cocktail approach for in vivo phenotyping of 5 major CYP450 isoenzymes: development of an effective sampling, extraction, and analytical procedure and pilot study with comparative genotyping.

Pub. Date : 2012 Aug

PMID : 21885687






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In this study, the authors developed a phenotyping method for CYP1A2, 2C9, 2C19, 2D6, and 3A4 using a cocktail of 100 mg caffeine, 125 mg tolbutamide, 20 mg omeprazole, 30 mg dextromethorphan, and 2 mg midazolam. Dextromethorphan cytochrome P450 family 1 subfamily A member 2 Homo sapiens