Title : Ethanol promotes chemically induced oral cancer in mice through activation of the 5-lipoxygenase pathway of arachidonic acid metabolism.

Pub. Date : 2011 Nov

PMID : 21881027






2 Functional Relationships(s)
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1 Expression of 5-lipoxygenase (5-Lox) and cyclooxygenase 2 (Cox-2) was increased in dysplasia and SCC of 4NQO-treated tongues and further enhanced by ethanol. 4-Nitroquinoline-1-oxide prostaglandin-endoperoxide synthase 2 Mus musculus
2 Expression of 5-lipoxygenase (5-Lox) and cyclooxygenase 2 (Cox-2) was increased in dysplasia and SCC of 4NQO-treated tongues and further enhanced by ethanol. 4-Nitroquinoline-1-oxide prostaglandin-endoperoxide synthase 2 Mus musculus