Title : Inhibition of p34cdc2 kinase activity by etoposide or irradiation as a mechanism of G2 arrest in Chinese hamster ovary cells.

Pub. Date : 1990 Jun 15

PMID : 2187601






4 Functional Relationships(s)
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Protein Name
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1 Inhibition of p34cdc2 kinase activity by etoposide or irradiation as a mechanism of G2 arrest in Chinese hamster ovary cells. Etoposide cyclin dependent kinase 1 Homo sapiens
2 Treatment of either asynchronous CHO cells or an enriched G2 population with the antitumor agent, etoposide, results in rapid inhibition of immunoprecipitated p34cdc2 kinase activity, which is not due to a direct effect of drug upon the enzyme. Etoposide cyclin dependent kinase 1 Homo sapiens
3 p34cdc2 kinase activity recovers as cells arrest in G2 and a second etoposide treatment further inhibits p34cdc2 kinase activity and prolongs G2 arrest. Etoposide cyclin dependent kinase 1 Homo sapiens
4 p34cdc2 kinase activity recovers as cells arrest in G2 and a second etoposide treatment further inhibits p34cdc2 kinase activity and prolongs G2 arrest. Etoposide cyclin dependent kinase 1 Homo sapiens