Title : PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains.

Pub. Date : 2011 Aug 30

PMID : 21873248






1 Functional Relationships(s)
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1 Alteration of this compartmentalization, either by genetic targeting or ceramide-induced recruitment of PTEN to rafts, abolishes the activity of the entire pathway. Ceramides phosphatase and tensin homolog Homo sapiens