Pub. Date : 2011 Oct 4
PMID : 21870821
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aromatase/cyclases (ARO/CYCs) are an important component of the type II polyketide synthase (PKS) and help fold the polyketide for regiospecific cyclizations of the first ring and/or aromatization, promoting two commonly observed first-ring cyclization patterns for the bacterial type II PKSs: C7-C12 and C9-C14. | Polyketides | cytochrome P450 family 19 subfamily A member 1 | Homo sapiens |
| 2 | In this work, we present the 2.4 A crystal structure of ZhuI, a C7-C12-specific first-ring ARO/CYC from the type II PKS pathway responsible for the production of the R1128 polyketides. | Polyketides | cytochrome P450 family 19 subfamily A member 1 | Homo sapiens |