Title : Blocking Daxx trafficking attenuates neuronal cell death following ischemia/reperfusion in rat hippocampus CA1 region.

Pub. Date : 2011 Nov

PMID : 21843499






1 Functional Relationships(s)
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1 We found the treatment of SP600125 or NAC could decrease the activation of Ask1 during ischemia/reperfusion and suppress the assembly of the Fas Daxx Ask1 signaling module, and in succession inhibit JNK activation and c-Jun phosphorylation. Acetylcysteine mitogen-activated protein kinase 8 Rattus norvegicus