Title : Proliferation-inhibiting and apoptosis-inducing effects of ursolic acid and oleanolic acid on multi-drug resistance cancer cells in vitro.

Pub. Date : 2011 Aug

PMID : 21826595






1 Functional Relationships(s)
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1 After SW480 cells were treated by UA at the concentrations of 0-40 mumol/L for 48 h, FCM showed that annexin V (AV) positive cells and hypodiploid peak ratio increased along with the increase in the drug"s concentrations; and Western blot found that expressions of Bcl-2, Bcl-xL and survivin decreased in a concentration-dependent manner. ursolic acid annexin A5 Homo sapiens