Title : Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.

Pub. Date : 2011 Nov

PMID : 21821735






4 Functional Relationships(s)
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1 Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6. Cannabidiol cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 CBD competitively inhibited the CYP2D6 activities with the apparent K(i) values of 1.16 to 2.69 muM. Cannabidiol cytochrome P450 family 2 subfamily D member 6 Homo sapiens
3 To clarify the structural requirement for CBD-mediated CYP2D6 inhibition, effects of CBD-related compounds on the AMMC O-demethylase activity of recombinant CYP2D6 were examined. Cannabidiol cytochrome P450 family 2 subfamily D member 6 Homo sapiens
4 To clarify the structural requirement for CBD-mediated CYP2D6 inhibition, effects of CBD-related compounds on the AMMC O-demethylase activity of recombinant CYP2D6 were examined. Cannabidiol cytochrome P450 family 2 subfamily D member 6 Homo sapiens