Title : Notch signaling may negatively regulate neonatal rat cardiac fibroblast-myofibroblast transformation.

Pub. Date : 2011

PMID : 21812518






1 Functional Relationships(s)
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1 The results showed that: (1) Notch receptor 1, 2, 3 and 4 were all expressed in CFs; (2) DAPT promoted CMT in a time-dependent manner; (3) During the period of CMT induced by TGF-beta1, expressions of Notch receptor 1, 3 and 4 in CFs were down-regulated, whereas there was no change for Notch receptor 2. dapt transforming growth factor, beta 1 Rattus norvegicus