Title : Targeting the ABCB4 gene to control cholesterol homeostasis.

Pub. Date : 2011 Oct

PMID : 21801087






1 Functional Relationships(s)
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1 INTRODUCTION: Multidrug resistance 3 (MDR3) P-glycoprotein is a lipid floppase that is encoded by the ATP-binding cassette sub-family B member 4 (ABCB4) gene and plays a crucial role in proper bile formation by transporting phosphatidylcholine across the canalicular plasma membrane of the hepatocyte into bile. Phosphatidylcholines ATP binding cassette subfamily B member 1 Homo sapiens