Title : Beta-amyloid peptide variants in brains and cerebrospinal fluid from amyloid precursor protein (APP) transgenic mice: comparison with human Alzheimer amyloid.

Pub. Date : 2011 Sep 30

PMID : 21795681






3 Functional Relationships(s)
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1 Using one- and two-dimensional gel electrophoresis, immunoblotting, and mass spectrometry, we identified the Abeta peptides Abeta(1-40), -(1-42), -(1-39), -(1-38), -(1-37), -(2-40), and -(3-40) as well as minor amounts of pyroglutamate-modified Abeta (Abeta(N3pE)) and endogenous murine Abeta in brains from 24-month-old mice. Pyrrolidonecarboxylic Acid amyloid beta (A4) precursor protein Mus musculus
2 Using one- and two-dimensional gel electrophoresis, immunoblotting, and mass spectrometry, we identified the Abeta peptides Abeta(1-40), -(1-42), -(1-39), -(1-38), -(1-37), -(2-40), and -(3-40) as well as minor amounts of pyroglutamate-modified Abeta (Abeta(N3pE)) and endogenous murine Abeta in brains from 24-month-old mice. Pyrrolidonecarboxylic Acid amyloid beta (A4) precursor protein Mus musculus
3 Using one- and two-dimensional gel electrophoresis, immunoblotting, and mass spectrometry, we identified the Abeta peptides Abeta(1-40), -(1-42), -(1-39), -(1-38), -(1-37), -(2-40), and -(3-40) as well as minor amounts of pyroglutamate-modified Abeta (Abeta(N3pE)) and endogenous murine Abeta in brains from 24-month-old mice. Pyrrolidonecarboxylic Acid amyloid beta (A4) precursor protein Mus musculus