Title : Immunization with DNA topoisomerase I and Freund's complete adjuvant induces skin and lung fibrosis and autoimmunity via interleukin-6 signaling.

Pub. Date : 2011 Nov

PMID : 21792823






2 Functional Relationships(s)
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1 RESULTS: Treatment with topo I and CFA, in contrast to treatment with topo I and IFA, induced skin and lung fibrosis with increased interleukin-6 (IL-6), transforming growth factor beta1, and IL-17 production and decreased IL-10 production. 3-chloro-4-fluoroaniline interleukin 6 Mus musculus
2 RESULTS: Treatment with topo I and CFA, in contrast to treatment with topo I and IFA, induced skin and lung fibrosis with increased interleukin-6 (IL-6), transforming growth factor beta1, and IL-17 production and decreased IL-10 production. 3-chloro-4-fluoroaniline interleukin 6 Mus musculus