Title : Lapatinib, a preventive/therapeutic agent against mammary cancer, suppresses RTK-mediated signaling through multiple signaling pathways.

Pub. Date : 2011 Aug

PMID : 21791570






1 Functional Relationships(s)
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1 Lapatinib effectively suppressed the abundance of HER2, phosphorylated HER2 (Tyr1221/1222), and phosphorylated EGFR (Tyr1173, Tyr1110) compared with tumors from untreated rats. Lapatinib epidermal growth factor receptor Rattus norvegicus